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Discussion on Procaine penicillan reaction, continues?
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New Member: Clabber
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Posted on Sunday, Aug 8, 2004 - 10:48 pm:
Hi, I have a 12 yr old TB who was receiving penicillan/dexamethasone shots for a deep cut/puncture. On the 4th day he had a classic toxic reaction to the procaine, I believe. I have seen this reaction before years ago, and although I was careful to draw back on the syringe before injection, I've been told it is still possible to have a reaction. My question is would a horse continue to have a similar reaction weeks later when not receiving any medication? My TB has several times had a brief episode similar to the shot reaction. The first was one week after the initial reaction. Then approximately one month after he had a very mild episode while being shod. Today another two weeks later he had another reaction while tied in the barn aisle. The episodes are relatively mild. His eyes become white rimmed, he seems very inward focused, his head is somewhat lowered, he is slightly trembly and unsteady, easily agitated. He quickly returns to normal. Today 10-15 minutes after his episode I was scratching his forelock and over his poll. He seemed to like it, but then seemed to go into another episode. He quickly returned to normal again. Between these episodes he has been normal, working well in dressage 2nd/3rd level. In retrospect he has possibly been slightly more spooky than is normal. I'm headed for the vets tomorrow, what should I ask that I might overlook? Any suggestions on what this could be? Thanks Marti
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Moderator: DrO
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Posted on Monday, Aug 9, 2004 - 7:35 am:
Marti I have not heard of a chronic problem with this type reaction. I am uncertain these are procaine toxicity reactions which are usually characterised as causing extreme excitement and that is the mild form, as it worsens it may lead to seizures and collapse. Yours sounds a bit more like narcolepsy: could this have been brought on by the procaine reaction(?), I don't know. For more on narcolepsy see Equine Diseases » Nervous System » Narcolepsy, Cataplexy, and Fainting. DrO
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