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Discussion on 3 months on three months off cimeditine
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Member:
Fpony
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Posted on Tuesday, Dec 7, 2004 - 7:54 am:
Hi dr. O, I'm treating my 20 y/o gray pony's melanoma with 1000mg three times a day. We started in july and several tumors on his anus have shrunk.the most significant was a 1 1/2 inch sized tumor that became flat after two months. My vet wants me to treat for 6 months to a year. I had also heard of doing 3 months on and 3 months off but don't know the rational. It appears that there has been no change for the last month. Does the stomach or intestine need a break from the Cimeditine? Does it upset the natural flura of the intestine? Thanks, Kim and Foxy
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Moderator:
DrO
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Posted on Tuesday, Dec 7, 2004 - 7:18 pm:
Hello Kim,
Congrats on the cimetidine helping. Apparently this medication is well tolerated for very long periods of time so there is no need to rest. As long as there is improvement I continue using it. I usually use 30-60 day checks and a ruler for careful measurement. Then we check every 6 months and start it back if they start to enlarge.
DrO
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Member:
Fpony
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Posted on Wednesday, May 11, 2005 - 9:46 pm:
Hi Dr. O,
It has now been 10 minths of treatment. It doesn't appear to be making any changes so i'm thinking of stopping except the opthamologist at Tufts discovered what she beleives is melanoma in his good eye. Dec 30,04 foxy had his other eye removed due to uveitis and glaucoma.We had been struggling to get his eye under control since July. So i'm nervous to stop the cimetidine for fear of loosing the other eye to melenoma. Can they grow that quickly that we would catch it in time to start the cimetidine again? If there has been no noticable change in the last few months could the med be still keeping it from growing but not shrinking?
Here are some pictures of the tumors on his anus 7/04 and then 9/04. I will take some more to compare again.
For some reason the upload doesn't seem to be working?? Can you tell me what should happen when i click upload?
Kim
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Moderator:
DrO
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Posted on Thursday, May 12, 2005 - 7:10 am:
Hello Kim,
Concerning the upload, you should get a pop-up with further instructions. I just pushed the button and it popped up, do you have a pop-up blocker?
The tumors will usually start growing again following discontinuing but it may be quickly or they may be quiet for months. I have had good luck stopping the tumors when regrowth starts again following discontinuing use but cannot quess if you might be able to catch the eye tumor in time.
DrO
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Member:
Fpony
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Posted on Thursday, May 12, 2005 - 8:29 am:
Sounds like i should just keep him on the Cimetidine.
the pop up window did appear and I choose my file fine but then when I cklick the final upload botton nothing happened. I made the pic smaller and then it worked!
 July 04
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Member:
Fpony
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Posted on Thursday, May 12, 2005 - 8:33 am:
Hope the pics don't offend anyone. The July pic isn't at it's worse. This tumor was really oozing I was very lucky he didn't get any secondary issues. It got worse in Aug before it got better. My vet didn't think the med was helping but I'm glad I stuck it out.
Kim
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Member:
Hboggini
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Posted on Thursday, May 12, 2005 - 8:56 am:
Hi
I have a gray tb mare who has had melanomas since she was 6yrs. They are under her tail and around her anus and vagina. I also rxed with cimetidine but found it did nothing. I then tried doing some homeopathy which seemed to slow the growths. Its worth a try if nothing else works
Heidi
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Member:
Fpony
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Posted on Thursday, May 12, 2005 - 9:18 am:
Heidi,
What kind of homeopathy?
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Member:
Hboggini
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Posted on Thursday, May 12, 2005 - 11:37 am:
I used carcinosom and arsinica. The contact vet to call is Dr Harmon, through Harmony clinic. We changed feed diet and she gets daily flaxseed as well. The web site I believe is Harmonyclinic .com
Good luck
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Member:
Fpony
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Posted on Friday, Aug 19, 2005 - 9:01 pm:
My pony was sick in July and I stopped the cimetidine as i was feeding other meds and I was having a hard time with the schedule. I figuired it wasn't really helping at this point. Well, the bottle stated to smell so i completely discontinued it. His tumors starrted growing again! It's hard to tell if it would have happen any way as the one in his lip had gotten bigger on it's own but now the shoulder one has grown in the last two weeks.
I couldn't find harmonyclinic. Dr. O have you heard of this treatment? His eye and the lip are of concern as the lip is interfering with his teeth. Would laser surgery be worth while at age 21? Would it be as hard on him as when his eye was removed? Kim
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Moderator:
DrO
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Posted on Saturday, Aug 20, 2005 - 10:34 am:
No and if truly homeopathic not worth trying. Herbal therapies (which are not homeopathic) for cancer are at best of uncertain value. I would get a new bottle of cimetidine and dose carefully following the high end dosages recommended in the article.
DrO
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Member:
Fpony
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Posted on Saturday, Aug 20, 2005 - 11:11 am:
Thanks Dr. O.
What about laser surgery on the tumor on his lip that is interfering with chewing? The equine dentist can make him a bit more comfortable but he still catches it sometimes. There is a pocket which catches food. My concern was first putting him under for surgery and secondly, will the tissue heal comfortablly-meaning will he end up with neuroma or scarring that is painful? Kim
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Moderator:
DrO
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Posted on Sunday, Aug 21, 2005 - 8:29 am:
I think the concerns about painful neuroma or scar are not likely and I am uncertain general anesthesia is required. Very heavy sedation in a good set of stocks might be enough.
DrO
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