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Discussion on UTI and Cranberries
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Member:
jynx2501
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Posted on Tuesday, Jan 29, 2008 - 1:09 pm:
Dr. O,
Do cranberries work the same for horses as they do for women and elephants? Can you use crushed whole cranberries rather than the juice form?
As always, your feedback is very much appreciated. I'm not sure what we would do if we didn't have you to put our oddball questions to.
Jynx
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Moderator:
DrO
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Posted on Tuesday, Jan 29, 2008 - 8:01 pm:
Actually the role of cranberries and human urinary tract infections is a bit uncertain. We have no work in horses at all.
DrO
Eur J Clin Microbiol Infect Dis. 2007 Nov;26(11):767-76.
The cranberry and the urinary tract.
Cimolai N, Cimolai T.
Department of Pathology and Laboratory Medicine, Faculty of Medicine, The University of British Columbia, Vancouver, BC, Canada.
Cranberry products have been heralded as natural treatments for urinary tract infections (UTIs) and have been widely used for this purpose. Current evidence favours an antibacterial role for the cranberry's natural polyphenols or tannins. Although limited species- and strain-specific direct inhibition has been determined in vitro, it has been suggested that a key mechanism of inhibition, especially for the abundant uropathogenic E. coli, relies on anti-adhesion properties. Many studies of prevention have been complicated due to the enrollment of patients who have had complicated urinary tracts, and outcomes have not been consistently favourable. In contrast, significant prevention has been shown for acute cystitis among high-risk young females. While reasonably well tolerated and deplete from side effects, further scientific work is required to better place the role of cranberry products in the management of UTIs. Progress in this area has set the stage for further hypothesis testing studies.
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Member:
jynx2501
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Posted on Wednesday, Jan 30, 2008 - 5:09 pm:
Thank you, Dr. O. for your response. You are a gem....
Has anybody else out there tried crushed cranberries or juice to help with UTI's in their horses?
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