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Discussion on Research Summary: Rabies and Post Exposure Treatment
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Moderator:
DrO
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Posted on Saturday, Jan 8, 2011 - 4:42 pm:
Post exposure vaccination as a way to prevent rabies in exposed unvaccinated pets and livestock use to frowned upon. The concern was possible vaccine breakthrough and exposure of handlers to rabies. Recent large well conducted surveys, like this one, suggest some protocols may be effective. For more on prevention, vaccination, and protocol particulars for rabies see the article.
DrO
J Am Vet Med Assoc. 2010 Dec 15;237(12):1395-401.
Evaluation of a postexposure rabies prophylaxis protocol for domestic animals in Texas: 2000-2009.
Wilson PJ, Oertli EH, Hunt PR, Sidwa TJ.
Texas Department of State Health Services, Zoonosis Control Branch, MC 1956, PO Box 149347, Austin, TX 78714.
Abstract
Objective-To determine whether postexposure rabies prophylaxis (PEP) in domestic animals, as mandated in Texas, has continued to be effective and to evaluate preexposure or postexposure vaccination failures from 2000 through 2009. Design-Retrospective case series. Animals-1,014 unvaccinated domestic animals (769 dogs, 126 cats, 72 horses, 39 cattle, 3 sheep, 4 goats, and 1 llama) that received PEP and 12 vaccinated domestic animals (7 dogs and 5 cats) with possible failure of protection. Procedures-Zoonotic incident reports from 2000 through 2009 were reviewed for information regarding unvaccinated domestic animals that received PEP in accordance with the state protocol after exposure to a laboratory-confirmed rabid animal; reports also were reviewed for any preexposure or postexposure vaccination failures. The state-required PEP protocol was as follows: immediately vaccinate the animal against rabies, isolate the animal for 90 days, and administer booster vaccinations during the third and eighth weeks of the isolation period. Results-From 2000 through 2009, 1,014 animals received PEP; no failures were recorded. One preexposure vaccination failure was recorded. Conclusions and Clinical Relevance-The Texas PEP protocol was used during the 10-year period.
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