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  Discussion on Research: Corneal degeneration vs Calcific Band Keratopathy
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Posted on Sunday, Jan 24, 2016 - 2:47 pm:

Vet Ophthalmol. 2016 Jan 15.
Comparison of corneal degeneration and calcific band keratopathy from 2000 to 2013 in 69 horses.
Berryhill EH1, Thomasy SM2, Kass PH3, Reilly CM4, Good KL2, Hollingsworth SR2, Maggs DJ2, Magdesian KG5, Pusterla N5.

Author information:
1Veterinary Medical Teaching Hospital, University of California-Davis, Davis, CA, 95616, USA.
2 Department of Surgical and Radiological Sciences, University of California-Davis, Davis, CA, 95616, USA.
3Department of Population Health and Reproduction, University of California-Davis, Davis, CA, 95616, USA.
4Department of Pathology, Microbiology and Immunology, School of Veterinary Medicine, University of California-Davis, Davis, CA, 95616, USA.
5Department of Medicine and Epidemiology, University of California-Davis, Davis, CA, 95616, USA.

Abstract
OBJECTIVE:

To compare signalment, presentation, treatment, and outcome in horses diagnosed with corneal degeneration (CD) or calcific band keratopathy (CBK) at a referral hospital.
ANIMALS STUDIED:

Sixty-nine horses (87 eyes) diagnosed with either CD or CBK.
PROCEDURES:

Medical records of horses diagnosed with CD or CBK at the University of California-Davis Veterinary Medical Teaching Hospital (UCD-VMTH) between 2000 and 2013 were reviewed. Signalment, concurrent ophthalmic diagnoses, previous therapies, diagnostic tests, systemic diagnoses, treatment, follow-up, and outcomes were compared between horses diagnosed with CD or CBK. Age, breed, and gender were compared between the CD/CBK and UCD-VMTH populations.
RESULTS:

Thirty-three horses (42 eyes) and 36 horses (45 eyes) were diagnosed with CD and CBK, respectively. Horses with CD or CBK were significantly older (P < 0.001) than the UCD-VMTH population with a median age of 16 or 18 years, respectively. Appaloosas were significantly overrepresented in the CD/CBK population (33%) in comparison with the UCD-VMTH population (1.8%, P < 0.001). Equine recurrent uveitis was concurrently diagnosed in 67% and 84% of horses with CD or CBK, respectively. Pituitary pars intermedia dysfunction (PPID) was diagnosed significantly less often in horses with CD vs. CBK (P = 0.03). Chemical chelation with ethylenediaminetetraacetic acid was performed significantly less frequently in horses diagnosed with CD (7.1%) vs. CBK (31.1% of eyes) (P = 0.012).
CONCLUSIONS:

Despite some differences, equine CD and CBK are relatively similar conditions and may represent a continuum of disease severity. Horses with PPID should be monitored closely for corneal disease including CBK.
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