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Discussion on Research: Fibrosis of the Bowel Wall Associated with Colic
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Moderator: DrO
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Posted on Tuesday, Feb 9, 2016 - 11:06 am:
It is too early to know is this a cause or effect of the colic but the fairly high incidence suggests that this is an important finding in need of further research. DrO J Comp Pathol. 2016 Feb 3. Idiopathic Fibrosis of the Tunica Muscularis of the Large Intestine in Five Horses with Colic. Mair TS1, Sherlock CE2, Fews D3, Harley R3, Pearson GR3. Author information: 1Bell Equine Veterinary Clinic, Mereworth, Maidstone, Kent, UK. 2Bell Equine Veterinary Clinic, Mereworth, Maidstone, Kent, UK. 3School of Veterinary Sciences, University of Bristol, Langford House, Langford, Bristol, UK. Abstract Histological evidence of fibrosis affecting the outer layer of the large intestinal tunica muscularis was identified in five of 32 horses affected by colic. In three cases, foci of pale eosinophilia and vacuolation of myocytes were observed. These findings are suggestive of a degenerative and fibrotic abnormality in the outer layer of the tunica muscularis of the large intestinal smooth muscle of some horses with colic.
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