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Discussion on DMG 2000 powder ?
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Member:
Dres
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Posted on Friday, May 13, 2005 - 5:03 pm:
Dr. O or anyone else, have you heard of this supplement? My understanding is that the endurance riders use it to help avoid TIE UP... any truth in this supplement..?
N,N-Dimethylgltcine HyDrOchloride in a sweet palatable base...
contains, not less than: DMG 2000mg
""DMG is an active metabolite, vitamin like nutrient, known for its ability to produce measured increases in athletic performance , energy, stamina, endurance and muscle recovery time while improving oxygen utilization and delaying muscle fatigue.. DMG has been found to retard lactic acid accumulation , the compound that forms in the muscle and causes tiredness...
On the first day God created horses, on the second day he painted them with SPOTS..
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Member:
Sunny66
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Posted on Friday, May 13, 2005 - 11:09 pm:
Hi Ann,
I have never heard of that one, but our resident feed store  owner said he knows a lot of endurance riders that give selenium/vit e. for that purpose.
I started my guy on it last week, and his belly has quit being so dang tight...
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Moderator:
DrO
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Posted on Saturday, May 14, 2005 - 7:36 am:
DMG has been around a long time and none of the above statements supported by scientific work:
Vet Rec. 1989 Sep 2;125(10):268-71.
Effects of N,N-dimethylglycine on cardiorespiratory function and lactate production in thoroughbred horses performing incremental treadmill exercise.
Rose RJ, Schlierf HA, Knight PK, Plummer C, Davis M, Ray SP.
Department of Veterinary Clinical Sciences, University of Sydney, New South Wales, Australia.
In a crossover study, either a placebo paste or N,N-dimethylglycine was administered orally at a dose rate of 1.2 mg/kg twice daily for five days to six thoroughbred horses, with bodyweights ranging from 424 to 492 kg. Using previously determined regression equations for oxygen uptake (VO2) against speed for each horse, a standardised exercise test was given with speeds equivalent to fixed percentages of the maximum oxygen uptake (VO2max). The test consisted of two minutes at speeds equivalent to approximately 40 per cent and 50 per cent VO2max, and one minute at speeds that produced approximately 60, 70, 80, 90 and 100 per cent VO2max. During the last five seconds of each exercise stage, the values of VO2, carbon dioxide production (VCO2), heart rate, arterial blood and plasma lactate concentrations, arterial blood gases and pH were measured. Before and immediately after the exercise test, muscle biopsies were collected from the middle gluteal muscle to determine the muscle lactate concentrations. The administration of N,N-dimethylglycine produced no significant differences in any of the measured values, and it is concluded that the compound has no beneficial effects on cardiorespiratory function or lactate production in the exercising horse.
DrO
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