New Article: Polyacrylamide Hydrogel (PAAG or PAHG), for Arthritis in Horses

Polyacrylamide hydrogel (Arthramid® Vet and Noltrex®Vet) is used in the treatment of mild to moderate osteoarthritis in both humans and horses. Similar to hyaluronate, polyacrylamide hydrogel (PAAG or PAHG) is injected directly into the joint and is proposed to provide lubrication and cushioning to the joint to help restore a more normal joint environment. A significant difference is PAAG does not degrade as quickly over time. In this way they may provide significant long term therapy and support for compromised joints. On the other hand one proposed mechanism of HA is that it’s degradation helps lower, use up, the inflammatory chemicals causing the arthritis. This article looks at the state of human and equine research including, clinical results, proposed mechanisms of action, precautions, and proposed dosages. Looking at the information currently available these products look promising, even exciting.

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