Influence of failure of passive transfer serum selenium, copper, zinc

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Serum concentrations of selenium, copper, and zinc in neonatal foals: Influence of failure of passive transfer and age-related changes
Can Vet J. 2024 May;65(5):481-487.
Authors
Lydia T Stahl 1 , Anja Müller 1 , Judith Krohn 1 , Kathrin Büttner 1 , Axel Wehrend 1
Affiliation

1 Veterinary Clinic for Reproductive Medicine and Neonatology, Justus-Liebig-University Giessen, Frankfurter Str. 106, 35392 Gießen, Germany (Stahl, Krohn, Wehrend); Vet Med Labor GmbH IDEXX Laboratories, Humboldtstrasse 2, 70806 Kornwestheim, Germany (Müller); Unit for Biomathematics, Justus-Liebig-University Giessen, Frankfurter Str. 95, 35392 Gießen, Germany (Büttner).

PMID: 38694739
PMCID: PMC11017931 (available on 2024-08-01)

Abstract
in English, French

Background: An adequate supply of trace elements is very important for equine neonates, as deficiencies can lead to health problems and even death.

Objective: This study investigated serum concentrations of selenium (Se), copper (Cu), and zinc (Zn) in neonatal foals up to the 8th day of life. The influences of disease, age, and failure of passive transfer (FPT) on these concentrations were analyzed.

Animals and procedure: Serum concentrations of Se, Cu, and Zn were determined from blood samples of 93 foals by means of inductively coupled plasma mass spectrometry. The foals were divided into 2 groups based on health status: clinically sick (n = 51) and clinically healthy (n = 42). The latter group was further divided into foals with FPT (n = 20) and those without (n = 22).

Results: Mean serum concentrations for Se, Cu, and Zn were 60 ± 40 μg/L, 0.25 ± 0.22 mg/L, and 605 ± 285 μg/L, respectively. A significant influence of age on serum Cu concentration was observed (P < 0.0001). No differences were observed between any of the serum concentrations in clinically sick and clinically healthy foals on the 1st day of life. The FPT status was not associated with reduced serum concentrations of Se, Cu, or Zn. Conclusion and clinical relevance: It is not necessary to supplement trace elements in all foals with FPT.