Assessment of tetanus revaccination in horses not vaccinated in the last year

Assessment of tetanus revaccination regimens in horses not vaccinated in the previous year

J Vet Med Sci . 2023 Jul 17;85(7):751-754. doi: 10.1292/jvms.23-0158. Epub 2023 Jun 1.
Yuta Kinoshita 1, Takashi Yamanaka 2, Kazumichi Kodaira 3, Hidekazu Niwa 1, Eri Uchida-Fujii 1, Takanori Ueno 1
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PMID: 37258221 PMCID: PMC10372253 DOI: 10.1292/jvms.23-0158
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Abstract
A two-dose revaccination against tetanus is recommended for horses over 2 years old in Japan with no history of vaccination in the previous year. Here, the need for two-dose revaccination was evaluated in terms of antibody titers for each vaccine type, namely monovalent or multivalent. There was no difference in antibody titers between one- and two-dose regimens for up to 1 year, except at 8 weeks with the multivalent vaccine, and all horses had sufficient antibody titers for 1 year of tetanus prophylaxis. These results suggest that one-dose revaccination, regardless of the vaccine type, is as effective as two-dose in preventing tetanus for at least 1 year in horses not vaccinated in the previous year.

Keywords: horse; tetanus; tetanus toxoid vaccine; vaccination number.