Aspirin

Acetylsalicylic Acid: Aspirin Use in Horses

by Robert N. Oglesby DVM

Introduction

Introduction » Use in Horses » Contraindications » Toxicity » Dosage » Associations and Drug Regulations » More Info & Discussions

To relieve minor pain (not colic) and fever. Aspirin can be used for a number of inflammatory problems and even substituted for bute in a pinch.

This article is about the contraindications, toxic effects, dosages, and association drug rules that apply to this medication.

Use in Horses

Introduction » Use in Horses » Contraindications » Toxicity » Dosage » Associations and Drug Regulations » More Info & Discussions

The half life of aspirin in plasma is seven minutes and it was no longer detectable in plasma after one and ½ hours. Ponies' may have a longer elimination time within one study the half life being 1 hour.

Aspirin differs from other NSAIDs in it ability to irreversibly inhibit cyclooxygenase. This has a profound affect on clotting time. Following treatment with aspirin, bleeding times (the time it takes for a wound to quit bleeding) where markedly increased for up to 48 hours.

Contraindications

Introduction » Use in Horses » Contraindications » Toxicity » Dosage » Associations and Drug Regulations » More Info & Discussions

                       
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