EHV-1, how immunity works

Creating populations of B cells that produce neutralizing EHV-1 mucosal antibodies is key to preventing systemic illness from Equine Herpes Virus-1. Also suggested is the possibility of introducing specific antibodies during outbreaks to introduce immediate immunity. DrO Equine herpesvirus type 1 (EHV-1) replication at the upper respiratory entry site is inhibited by neutralizing EHV-1-specific IgG1 … Read more

Equine grass sickness and abnormalities in the neuromuscular junctions

So the mystery deepens, if not botulism poisoning what? DrO Equine grass sickness is associated with major abnormalities in the ultrastructure of skeletal neuromuscular junctions Equine Vet J. 2024 Feb 1. doi: 10.1111/evj.14063. Online ahead of print. Authors Bruce C McGorum 1 , Tracey Davey 2 , Miranda C M Dosi 1 , John A … Read more

Effects of calcium supplementation to resuscitation fluids in endurance horses:

It remains unclear whether the addition of calcium to resuscitation fluids is on balance a good thing. It does suggest caution should be exercised for those horses with GI signs due to overexertion. DrO Effects of calcium supplementation to resuscitation fluids in endurance horses: A randomized, blinded, clinical trial J Vet Intern Med. 2023 May … Read more

Detection of maple toxins in mare’s milk

I have not seen a report of a foal illness from ingesting contaminated mare’s milk from maple ingestion. I presume that they are referring to the sycamore maple, a maple species with broad leaves somewhat resembling that of a sycamore tree. For more on this cause of myopathy see the article associated with this topic. … Read more

Hyperammonemia in 2 endurance horses

Wow this is the first I have heard of what is a pretty common problem in hard working horses: becoming depressed during maximal exertion. A number of blood dyscrasias come to mind (dehydration, electrolyte abnormalities, lowered blood ph) but this was not one. The blindness would be an unusual and alarming finding. Fortunately all these … Read more

Dysbiosis not observed in Canadian horse with free fecal liquid (FFL)

Chronic diarrhea without other signs of disease was an occasional and often frustrating problem I encountered in practice. The condition has become known as Free Fecal Liquid (FFL) or Fecal Water Syndrome (FWS). Scientific investigations into the problem have not been able to find a cause. Here was another unsuccessful attempt at identifying possible problems … Read more

Equine subchondral lucencies: Knowledge from the medial femoral condyle (stifle)

This article gives continued support for the idea that small lesions not associated with lameness do not require surgery. When to do surgery and which procedure still remains speculative but some reports suggest screw fixation may have the best chance of returning a horse to usable soundness. DrO Equine subchondral lucencies: Knowledge from the medial … Read more

Multinodular pulmonary fibrosis in horses: 46 cases (2009-2019)

I have encountered a few of these horses in practice. As found in this study, EHV-5 is associated with the disease and is thought to be the cause. The patients present very much like a horse with equine asthma (Heaves, COPD, or RAO) but are poorly responsive to steroids with a progressive worsening despite environmental … Read more

Theiler’s disease and equine biologics

We will use this report to emphasize the warning against heterologous equine biological products and their use in horses. Tetanus antitoxin jumps to mind and with the use of tetanus vaccine it’s use is not needed. Be sure to vaccinate your horse regularly for tetanus so there is no need for antitoxin. DrO Equine Parvovirus … Read more

Honey decreases the prevalence of incisional infection in horses

Intra-incisional medical grade honey decreases the prevalence of incisional infection in horses undergoing colic surgery: a prospective randomised controlled study Equine Vet J. 2020 Dec 19. Authors Kajsa Gustafsson 1 , Amos J Tatz 1 , Roni A Slavin 1 , Gila A Sutton 1 , Roee Dahan 1 , Wiessam Abu Ahmad 2 , … Read more