Overview of the causes of abortion in horses,

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      Invited Review: Overview of the causes of abortion in horses, their follow-up, and management
      Reprod Domest Anim. 2023 Jun 13.
      Authors
      Albertine Leon 1 2 , Clément Pillon 1 2 , Inès Tebourski 3 , Jean-François Bruyas 4 , Coralie Lupo 5
      Affiliations

      1 LABÉO, Equine health Research Department, Saint Contest, France.
      2 Normandie University, UNICAEN, UNIROUEN, Inserm UMR 1311 DYNAMICURE, Caen, France.
      3 Pharmacist, Evreux, France.
      4 Oniris, Nantes, France.
      5 RESPE-French network for surveillance of equine diseases, Saint Contest, France.

      Abstract

      Abortions in horses represent an important health and economic challenge for equine industry. Primary causes of abortion are divided in non-infectious and infectious. Non-infectious causes include abnormalities of foetal appendices (umbilical cord and placenta essentially), abnormalities of gestation, maternal and foetal origins. Infectious abortions are caused in almost cases by bacterial infections, followed by viruses, fungi, and parasites. New abortive pathogens (as Leptospira, Neospora caninum, Coxiella burnetii, Chlamydophila abortus, and) have been confirmed in equines by comparison already known for their abortive properties in human or in other species. Despite an increasing number of autopsies and continuous improvements in diagnostic tools, in management and surveillance, 20 to 40% of the causes of equine abortion remain unknown depending on the country. To increase the likelihood of a definitive diagnosis in cases of abortion and stillbirth in horses, new diagnostic approaches are needed. This article is protected by copyright. All rights reserved.

      Keywords: abortion; diagnostics; horse; infectious diseases; management; surveillance.

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