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This has been around for several months. It was flat, hairless, scaly. Now more raised with a more bubbly appearance. I treated it as rain rot recently, but it wasn’t acting like rain rot. Realized it was a sarcoid. Stopped disinfecting. Removed Desitin. Vet says she would have to be laid down for surgery, as it is inside the flap of skin in the groin between the belly and the thigh region, facing the teats. Going to discuss with surgeon. Vet is worried about getting the underlying tendrils with various treatments like lasers. However, I can lift the whole lesion up in fairly loose skin. It isn’t attached to anything. I’m opting for either doing nothing or applying a vet-prescribed cream since it is in a somewhat innocuous area away from eyes, etc. Any thoughts on Xxterra (blood root and zinc)? Suggestions? (This is the same Friesian who ate something toxic with a kidney issue.)
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Hello Laura,
I used Xxterra successfully to treat sarcoids but have no experience with imiquimod. I did find this interesting study that compared the two treatments and reviewed both favorably:Vet Dermatology.
2020 Dec;31(6):471-e126. doi: 10.1111/vde.12900. Epub 2020 Oct 5.Topical treatment of equine sarcoids with imiquimod 5% cream or Sanguinaria canadensis and zinc chloride – an open prospective study
Carina M Pettersson 1, Hans Broström 2, Patrice Humblot 2, Kerstin E Bergvall 2
Affiliations Expand
PMID: 33016520 DOI: 10.1111/vde.12900
Full text linksCiteAbstract in English, French, Spanish, German, Japanese, Chinese, Portuguese
Background: Equine sarcoids are the most prevalent skin neoplasm in horses worldwide. Although several treatments are available, none are consistently effective and recurrence is common.
Objectives: To evaluate the efficacy and safety of topical imiquimod 5% cream and Sanguinaria canadensis + zinc chloride for treatment of equine sarcoids and investigate possible systemic effects on distant untreated sarcoids.
Animals/tumours: Twenty-five client-owned horses with a total of 164 tumours were included in the study. Fifty-seven tumours were treated and 107 tumours were left untreated.
Methods and materials: Skin biopsy samples were collected from a minimum of one tumour per horse and the rest were diagnosed based on clinical appearance as likely sarcoids. Imiquimod 5% (A) was applied three times weekly, while Sanguinaria canadensis + zinc chloride (X) was applied every fourth day after a six day daily initiation phase. Treatment continued until clinical remission or for a maximum of 45 weeks, with a long follow-up period (mean 34 months). Skin biopsy samples of sarcoid lesions were re-taken before treatment termination and at follow-up if the owner gave consent.
Results: Complete remission was recorded in 84.4% (A) and 75.0% (X) of the tumours. Relapse was recorded in 7.3% (A) and 21.4% (X). Spontaneous remission was observed in 1.9% of untreated tumours. No systemic effect on untreated tumours was detected. During treatment varying degrees of local inflammatory reaction were common.
Conclusions and clinical relevance: Both treatments were considered effective and safe. Smaller tumours responded more favourably to treatment. Relapse rate was low and not observed in sarcoids with repeat biopsies before treatment termination.
© 2020 The Authors. Veterinary Dermatology published by John Wiley & Sons Ltd on behalf of the European Society of Veterinary Dermatology and the American College of Veterinary Dermatology.
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